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KMID : 1103720110650040373
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Journal of the Korean Society of Radiology
2011 Volume.65 No. 4 p.373 ~ p.379
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CT Fluoroscopy-Guided Core Biopsy for Diagnosis of Small (≤ 20 mm) Pulmonary Nodules
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Lee Hye-Lan
Kim Yoon-Kyung
Woo Ok-Hee
Yong Hwan-Seok
Kang Eun-Young
Kim Hyun-Koo
Shin Bong-Kyung
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Abstract
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Purpose:To evaluate the efficacy of CT fluoroscopy-guided core biopsy of small pulmonary nodules.
Materials and Methods :This study included 62 patients (35 men, 27 women; age range, 36-85 years) that had a small (≤ 20 mm) pulmonary nodule and underwent CT fluoroscopy-guided core biopsy. The overall diagnostic accuracy and complication rate were calculated. The diagnostic accuracy was compared between two groups according to the nodule size (≤ 10 mm vs. > 10 mm), and nodule density (solid vs. subsolid).
Results:Malignant or premalignant lesions were finally diagnosed in 39 patients; 36 true-positive and three false-negative findings (sensitivity, 92%). A benign lesion was finally diagnosed in 23 patients, with no false-positive results (specificity, 100%). The overall diagnostic accuracy was 95%. The sensitivity and diagnostic accuracy were 85% and 91% for nodules ≤ 10 mm, and 96% and 97% for nodules > 10 mm (p > 0.05). The sensitivity and diagnostic accuracy were 93% and 96% in the solid group and 90% and 92% in the subsolid group (p > 0.05). Seventeen (27%) patients had a pneumothorax and two (3%) required a closed thoracostomy.
Conclusion:CT fluoroscopy-guided core biopsy of small pulmonary nodules yields high diagnostic accuracy with acceptable complication rates.
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KEYWORD
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Computed Tomography , Computed Tomography Fluoroscopy , Biopsy, Needle , Lung Neoplasms , Pulmonary Nodules
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